2003 Quadrennial Meeting of the American Society or Stereotactic and Functional Neurosurgery New York City

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Sunday, May 18

Pre-Meeting Workshops

8:00 am - 12:00 noon Workshop A: Movement Disorder Surgery
Chairs: Patrick Kelly, MD and Ali Rezai, MD
Workshop B: Pain
Chairs: David C. Henderson, MD and Kim J. Burchiel, MD
Workshop C: Image-Guided Surgery
Chairs: M. Peter Heilbrun, MD and Richard Bucholz, MD
12:00 noon – 1:30 pm Lunch
1:30 – 5:30 Workshop D: Radiosurgery
Chairs: Bruce E. Pollock, MD and Michael Schulder, MD
Workshop E: Epilepsy Surgery
Chairs: Nicholas M. Barbaro, MD and David W. Roberts, MD
7:00 Opening Cocktail Reception
Grand Ballroom
Monday, May 19 Scientific Program
7:00 am Registration and Continental Breakfast
7:30 Session 1: Open Scientific Session I
OPENING REMARKS
Chairs: Patrick J. Kelly, MD and Douglas S. Kondziolka, MD
7:40 Keynote Speaker: High Tech Surgery
Richard M. Satava, MD
8:10 The Robotics of Translating Thought into ActionKeynote Lecture:
Miguel A.L. Nicolelis, MD, PhD
Distinguished Service Award
Thomas Karger, MD and Philip Gildenberg, MD
8:45 Complications and Outcomes in 1428 Surgical Procedures for Epilepsy. A Comprehensive Review of Contemporary Epilepsy Surgery from One Epilepsy Center
Werner K. Doyle, MD
8:55 Cingulotomy for Intractable OCD: A Long Term Follow-Up Study
Rees Cosgrove, MD, FRCS(C); Darin Dougherty, MD; Lee Baer, PhD; Edwin Cassem, MD; Bruce Price, MD; Mike Jenike, MD; Scott Rauch, MD
9:10 Evaluation of CyberKnife Frameless Real-Time Image-Guided Stereotactic Radiosurgery for Spinal Lesions: A Series of 70 Patients
Peter C. Gerszten, MD; Steven A. Burton, MD; Cihat Ozhasoglu, PhD; William J. Vogel; MD; Barbara A. Atkins, RN; William C. Welch, MD, FACS; Shalom Kalnicki, MD
9:20 Fellow Award
Bilateral Anterior Thalamic Nucleus Lesions Are More Protective than Stimulation Against Pilocarpine Induced Seizures and Status Epilepticus
Clement Hamani, MD, PhD; Flavio I.S. Ewerton; Saulo M. Bonilha; Gerson Ballester, MD, PhD; Luiz E.A.M. Mello, MD, PhD; Andres M. Lozano, MD, PhD, FRCS(C)
9:35 Refreshment Break
10:15 INTRODUCTION OF THE ASSFN PRESIDENT
David Roberts, MD
10:20 Learning Stereotactic Surgery: With a Little Help from My Friends
Douglas S. Kondziolka, MD
10:40 Resident Award
Hemorrhagic Complications of Microelectrode-Guided DBS
Devin K. Binder, MD, PhD; Philip A. Starr, MD, PhD
10:50 Surgery for Parkinson Disease in the United States, 1996-2000: Practice Patterns, Short-Term Outcomes, and Hospital Charges in a Nationwide Sample
Emad N. Eskandar, MD; Rees G. Cosgrove, MD; Barker G. Fred, MD
11:00 Selective Peripheral Denervation for the Treatment of Intractable Spasmodic Torticollis: The Mayo Clinic Experience with 168 Patients
Aaron A. Cohen-Gadol, MD; Dudley H. Davis, MD; Eric Ahlskog, MD; Joseph Matsumoto; Mary Swansen, RN
11:15 Electrical Stimulation (ES) of Centromedian Thalamic Nucleus (CM) in Cases of Lennox-Gastaut Syndrome (LGS)
Marcos Velasco, PhD; Ana L. Velasco, MD; Fiacro Jimenez, PhD; Jose A. Hernandez, MSc; Francisco Velasco, MD
11:30 Multicenter Prospective Trial of Deep Brain Stimulation (DBS) for the Treatment of Intractable Obsessive Compulsive Disorder (OCD)
Ali R. Rezai, MD; Gerhard Friehs, MD; Nuttin Bart, MD; Rauch Scott, MD; Greenberg Benjamin, MDMalone Donald, MD; Cosyns Paul, MD; Rasmussen Steven, MD;
11:40 Non-Invasive Stimulating Lead and Extension Fault Localization Technique
Jay Shils, PhD; Michele Tagliati, MD; Joan Miravite, RNC; Ron L. Alterman, MD
11:50 Localization of Subcortical Targets with a Near-Infrared Probe: The Stereotactic Periscope
Cole A. Giller, MD, PhD; Dwight C. German, PhD; Hanli Liu, PhD
12:00 noon Lunch
Poster Viewing with Presenters
Monday, May 19 Session 2: Psychiatric Surgery/Open Scientific Session II
Chairs: G. Rees Cosgrove, MD and Ali Rezai, MD
1:30 pm Keynote Lecture:
Psychosurgery: Where Are We Going?
G. Rees Cosgrove, MD
2:05 Keynote Lecture: Question Period
2:15 Bilateral Anterior Capsulotomy for Refractory Obsessive-Compulsive Disorders
Alberto M.D. Aparicio, MD; Bartolome Oliver, MD, PhD; J. Gascon, MD; Marcel Garcia Bach, MD; J.L. Maestro de Leon, MD; Emilio Ayats, MD; Rodrigo Rodriguez, MD; P.A. Soler, MD
2:25 Bilateral Anterior Capsulotomy to Obsessive Compulsive Disorder
Jose A. Nasser, MD; Asdrubal Falavigna, MD; Fernando Ferraz, MD; Armando Alaminos, PhD; Helenice Charchat, PhD
2:40 Clinical Study for Alleviating Opiate Drug Abstinence by Method of Lesioning Nucleus Accumbens with Stereotactic Surgery
Gao Guodong, MD; Wang Xuelian, MD; He Shiming, MD; Wang Qinfeng, BA; Li Weixing, BA; Hou Fang, BSN; Liang Qinchuan, BA; Cheng Ling; Li Ailing; Zhang Hua, MD
2:50 Electrical Stimulation of the Interior Thalamic Peduncle (ITP) in the Treatment of Unipolar Depression
Francisco Velasco, MD; Fiacro Jimenez, PhD; Rafael Salin-Pascual, PhD; Jose A. Hernandez, MSc; Ana L. Velasco, MD; Marcos Velasco, PhD
3:00 Refreshment Break
3:30 Stimulation of the Subthalamic Nucleus is not Associated with Increased Striatal Dopamine Release as Assessed by (11-C)-Raclopride Displacement
Aviva Abosch, MD, PhD; Shitij Kapur, MD, PhD; Anthony E. Lang, MD; Doug Hussey, BSc; Elspeth Sime, RN; Janis Miyasaki, MD; Sylvain Houle, MD, PhD; Andres M. Lozano, MD, PhD
3:45 Deep Brain Stimulation in High-Field Intraoperative Magnetic Resonance Imaging Environment
Michael W.Y. Lee, FRCS, MBBS; Antonio A.F. DeSalles, MD, PhD.; Prof. Leonardo Frighetto, MD; Rodrigo C. Torres, MD; Eric Behnke, BS
3:55 Microvascular Decompression Surgery (MVD) in the United States, 1966-2000: Mortality, Morbidity, and the Effect of Hospital and Surgeon Volume
Steven N. Kalkanis, MD; Emad Eskandar, MD; Bob S. Carter, MD, PhD; Fred G. Barker II, MD
4:05 Unilateral Ablative Lesions of the Subthalamic Nucleus in Advanced Parkinson Disease: Long-Term Follow-up
Orhan Barlas, MD; Hasmet Hanagasi, MD; Murat Emre, MD
4:20 Stereotactic Interstitial Radiosurgery in Hypothalamic Hamartomas – Functional Outcome
Peter C. Warnke, MD; Brian Tedman, MD; David Chadwick, MD; Volker Homberg, MD; Andreas Schulze-Bonhage, MD; Christoph Ostertag, MD
4:30 The Role of the Basal Ganglia in Voluntary Movement Selection
Joseph S. Neimat, MD; Emad N. Eskandar, MD; John A. Assad, PhD
4:40 PTEN Anti-Oncogene Induces Reversion of Undifferentiated Pheochromocytoma Cells Away from a Neuronal Phenotype
Michael G. Kaplitt, MD, PhD; Jill Roberts, BS; Donald Pfaff, PhD; Sergei Moussatov, PhD
4:55 Neurotransplantation for Basal Ganglia Stroke: Results from a Phase 2 Trial
Douglas Kondziolka, MD; Gary Steinberg, MD; Lawrence Wechsler, MD; James Gebel, MD; Sharon DeCesare; Elaine Elder, DSc; Carolyn Meltzer, MD; Ross Zafonte, DO; David Tong, MD; Michael Marks, MD
5:05 Vagus Nerve Stimulation after Failed Cranial Surgery for Intractable Epilepsy: Results of the Cyberonics Patient Outcome Registry
Arun P. Amar, MD; Michael L.J. Apuzzo, MD
Tuesday, May 20 7:00 am Continental Breakfast
Session 3: Movement Disorder Surgery 1
Chairs: Phillip A. Starr, MD and Gordon Baltuch, MD
7:30 Keynote Lecture: Movement Disorder Surgery in the Future
Andres Lozano, MD, PhD
8:05 Keynote Lecture: Question Period
8:15 Surgical Complications of DBS Surgery: The Beth Israel Experience
David Poulad, MD; Jay Shils, PhD; Michele Tagliati, MD; Brendan Sullivan, PA-C; Ron Alterman, MD
8:27 Subthalamic Deep Brain Stimulation for Advanced Parkinson’s Disease: First 100 Cases, Indications, Technique, Results and Morbidity
Gordon H. Baltuch, MD, PhD; Jurg Jaggi, PhD; Andrew Siderowf, MD; Amy Colcher, MD; Howard Hurtig, MD; Matthew Stern, MD
8:39 Effect of High Frequency Stimulation of Subthalamic Nucleus on Subthalamic Neurons – An Intracellular Study
Kendall H. Lee, MD, PhD; Uhnoh Kim, PhD; David W. Roberts, MD
8:51 Deep Brain Stimulation of the Subthalamic Nucleus in Parkinson’s Disease: Correlation of Active Electrode Contacts with Intraoperative Microrecordings
Wolfgang Hamel, MD; Urban Fietzek, MD; Andre Morsnowski, MSc; Dieter Weinert, MD; Bettina Schrader, MD; Jens Volkmann, MD; Gunter Deuschl, MD, Prof; Dieter M. Iler, MD, Prof; H. Maximilian Mehdorn, MD, Prof
9:03 The Response of Specific PD Symptoms to Subthalamic Deep Brain Stimulation is Anatomically Discrete
Aubrey Okpaku, MD; Jay Shils, PhD; Michele Tagliati, MD; Joan Miravite, RNC; Ron L. Alterman, MD
9:15 Role of the Basal Ganglia in Movement Initiation and Suppression
Emad N. Eskandar, MD; John A. Assad, PhD
9:27 Refreshment Break
10:15 Motor Improvement’s Effect on Quality-of-Life Following Subthalamic Stimulation is Mediated by Changes in Depressive Symptomatology
Alexander I. Trster, PhD; Julie A. Fields, BA; Steven Wilkinson, MD; Rajesh Pahwa, MD; Willia, Koller, MD, PhD; Kelly Lyons, PhD
10:27 Long-Term Results of Thalamic Deep Brain Stimulation for Essential Tremor
Nicholas M. Wetjen, MD; John D. Putzke, PhD; Ryan J. Uitti, MD; Zbigniew K. Wszolek, MD; John J.A. Lucas, PhD; Margaret F. Turk, MSN; Robert E. Wharen, MD
10:39 Is Surgery Tremor Forever?
Ronald Tasker, MD, PhD, FRCS(C)
10:51 Progressive Improvement in Generalized Dystonia after Pallidal Deep Brain Stimulation
Michele Tagliati, MD; Jay Shills, PhD; Susan Bressman, MD; Joan Miravite, RNC; Ron A. Alterman, MD
11:03 Bilateral Electrical Stimulation of Prelemniscal Radiations in Advanced Parkinson’s Disease
Jose D. Carrillo-Ruiz, MSc; Francisco Velasco, MD; Fiacro Jimenez, MD; Jose A. Hernandez-Silverio, Prof; Carlos Arguelles, MD
11:15 Comparison of MRI Position and Size of STN to Schaltenbrand and Wahren Brain Atlas
Erich O. Richter, MD; Hoque Tasnuva, BSc; Saint-Cyr Jean, PhD; Lozano M. Andres, MD, PhD
11:27 Thalamic Stimulation in Patients with Multiple Sclerosis: Long Term Follow-Up
Michael Schulder, MD; Reza Karimi, BA
11:39 The Effects of Bilateral Subthalamic Nucleus Stimulation on Resting-State Cerebral Glucose Metabolism of Advanced Parkinson’s Disease
Bomin Sun, MD; Dianyou Li, MD; Jiankang Shen, MD; Yongbo Zhao, MD; Chuantao Zuo, MD; Yihui Guan, MD; Liqing Lang, MD; Wen Yu, MD; Shendi Chen, MD
11:51 Target Selection for Primary Dystonia Deep Brain Stimulation: GPi or STN
Bomin Sun, MD; Dianyou Li, MD; Chenyan Sun, MD; Daokuan Liu, MD; Yongbo Zhao, MD; Jiankang Shen, MD; Shendi Chen, MD
12:05 pm Lunch
Poster Viewing with Presenters
Tuesday, May 20 Session 4: Image-Guided Surgery
Chairs: M. Peter Heilbrun, MD and John R. Adler, Jr., MD
7:30 am Keynote Lecture: Where is Image Guidance Taking Us?
Richard D. Bucholz, MD
8:05 Keynote Lecture: Question Period
8:15 MR Safety in Patients with Implanted Neurostimulators: Update and Future Implications
Ashwini D. Sharan, MD; Ali R. Rezai, MD; Greg Hrdlicka, MBA, MSc; John Nyhenuis, PhD; Jean Tkach, PhD; Paul Ruggieri, MD; Ken Baker, PhD; Mike Phillips, MD
8:27 Stereotactic Image-Guided Surgery with Intra-Operative Portable CT
William D. Tobler, MD
8:39 The NASA Smart Probe Project for Automated Real-Time Multiple Microsensor Tissue Recognition
Russell J. Andrews, MD; Robert W. Mah, PhD
8:51 A Non-Contacting 3-D Digitizer for Use in Image-Guided Neurosurgery
Hai Sun, MSc; Hany Farid, PhD; David W. Roberts, MD; Kyle Rick, BA; aAlex Hartov, PhD; Keith Paulsen, PhD
9:03 Outcome Analysis in fMRI-Integrated Neuronavigation for Surgery in the Central Region
Rene Krishnan, MD; Hilal Yahya, MD; Andrea Szeleny, MD; Sabine Wagner, MD; Andreas Raabe, PhD; Volker Seifert, Prof.
9:15 Functional Magnetic Resonance Imaging in a Low Field Intraoperative Scanner
Michael Schulder, MD; Hooman Azmi, MD; Elizabeth Van Iperen, BA; Bharat Biswal, PhD
9:27 Refreshment Break
10:15 Image Guided Interstitial Laser Thermotherapy: A Canine Model Evaluated by Magnetic Resonance Imaging and Quantitative Autoradiography
Alexander Muacevic, MD; Michael Peller, MD; Dieter Berg, MD; Hanns-Juergen Reulen, MD, PhD; Joerg-Christian Tonn, MD, PhDLutz Ruprecht, MD; Freidrich W. Kreth, MD;
10:27 Use of a Frameless Stereotactic Robot for Movement Disorder Surgery
Thelekat, R.K. Varma, FRCS; Paul E. Eldridge, FRCS; Alan Forster, MD; Susan Fox, MD; Nick Fletcher, MD; Malcolm Steiger, MD; Patricia Littlechild, FRCS; Patricia Byrne, RN; Ann Sinnott, RN
10:39 Laser Surface Scanning Patient Registration in Neuronavigation
Rene Krishnan, MD; Andreas Raabe, PhD; Volker Seifert, Prof
10:51 Thalamic Stimulation for Essential Tremor: Relation of Lead Location to Outcome
Efstathios Papavassiliou, MD; Nicholas Barbaro, MD; Paul Larson, MD; Aviva Abosch, MD, PhD; William Marks Jr., MD; Kathleen Lambourn, PhD; Heidi Clay, RN; Susan Heath, CNRN, MS, RN; Philip Starr, MD, PhD
11:03 Beneficial Effect of Moderate Volume Reduction in Hematoma by Stereotactic Aspiration in Spontaneous Thalamic Hemorrhage
Chung-Ching Hsia, MD; Shinn-Zong Lin, MD, PhD
11:15 Longevity of Batteries in Internal Pulse Generators Used for Deep Brain Stimulation
Mohammed S. Bin-Mahfoodh, MBBS; Clement Hamani, MD, PhD; Elspeth Sime, RN; Andres M. Lozano, MD, PhD, FRCS(C)
11:27 Stereotactic-Guided Gamma Probe-Assisted Brain Tumor Microsurgical Resection
Osvaldo Vilela Filho, MD; Omar Carneiro Filho, MD
11:39 Precision and Accuracy New Robot Designed for Neurosurgery
Rene Krishnan, MD; Michael Zimmermann, PhD; Andreas Raabe, PhD; Volker Seifert, Prof
11:51 Influence of Stimulus Pacing on Language Lateralization with fMRI Using a Semantic Decision Task: Preliminary Results
Ann Tieleman, MD; Olivier Vandamme, MD; Karel Deblaere, MD; Jacques Caemaert, MD, PhD; Eric Achten, MD, PhD
12:05 pm Lunch
Poster Viewing with Presenters
Tuesday, May 20 Session 5: Pain
Chairs: Ronald Tasker, MD and Robert J. Coffey, MD
1:30 pm Keynote Lecture: Pain Surgery: Who, What, Where, When and Why
Kim J. Burchiel, MD
2:05 Keynote Lecture: Question Period
2:15 Spinal Cord Stimulator Adjustment to Maximize Implanted Battery Longevity: A Randomized, Controlled Trial Using a Computerized, Patient-Interactive Programmer
Richard North, MD; Sherri-Kae Calkins; David Brigham, BS; David Campbell, BS; Steven Piantadosi, MD, PhD; Michael Daly, MD; Bobby Day, MD; Giancarlo Barolat, MD
2:27 Bulbar Trigeminal Stereotactic Nucleotratotomy for Treatment of Facial Pain
Guilherme Lepski, MD; Paulo Henrique Aguiar, PhD; Valter Cescato, MD; Luis Rogano, MD; Manoel Teixeira, PhD
2:39 Repeat Gamma Knife Radiosurgery (GKRS) for Trigeminal Neuralgia (TN)
Ronald Brisman, MD
2:51 Longterm Outcome of Spinal Cord Stimulation and Hardware Complications
David G. Quigley, FRCS, MBBS; Jonathan Arnold; Paul R. Eldridge, FRCS, MBBS; Heather Cameron, BSc; Kate McIvor, BSc; John B. Miles, FRCS, MBBS; Thelkat R.K. Varma, FRCS, MBBS
3:03 Refreshment Break
3:33 Treatment of Atypical Facial Pain with Gamma Knife Trigeminal Rhizotomy
Rebekah C. Austin, MD; Thomas L. Ellis, MD; Volker W. Stieber, MD; Edward G. Shaw, MD; Stephen B. Tatter, MD, PhD
3:45 Frameless Radiosurgery for Trigeminal Neuralgia
Pantaleo Romanelli, MD; Gary Heit, MD, PhD; Steve Chang, MD; John Adler, MD; Dave Martin, MD
3:57 High-resolution MR Imaging in Patients with Primary Trigeminal Neuralgia: Comparison to Age-Matched Controls
Sam P. Javedan, MD; Adrian Harvey, BA; Andrew G. Shetter, MD; John P. Karis, MD; Bruce L. Dean, MD; Kris A. Smith, MD
4:09 Microvascular Decompression for Trigeminal Neuralgia in Patients with Multiple Sclerosis
Mohsen Javadpour, FRCS; Pataricia Littlechild, FRCS; Ajay K. Sinha, FRCS; Paul R. Eldridge, FRCS; Telekath R. Varma, FRCS
4:21 Chronic Pain After Spinal Cord Injury: Clinical Aspects and Results of Pharmacological, Physiatric and Functional Neurosurgical Treatments
Guilherme Lepski, MD; Luis Rogano, MD; Lin Yeng, PhD; Manoel Teixeira, PhD
4:33 Spinal Cord Stimulation (SCS) in the Treatment of Refractory Unilateral Limb Pain Syndrome (RULPS)
Abbay Kumar, MD; Sam Eljamel, MD
4:45 The Role of Pituitary Radiosurgery for the Management of Intractable Pain and Potential for Future Work
Motohiro Hayashi, MD; Takaomi Taira, MD; Roman Liscak, MD; C.-P. Yu, MD; Tomokatsu Hori, MD
Tuesday, May 20 Session 6: Movement Disorders Surgery 2
Chairs: Andres Lozano, MD, PhD and Aleksandar Beric, MD
1:30 pm Keynote Lecture: The History of the ASSFN and Movement Disorder Surgery
Philip Gildenberg, MD
2:05 Keynote Lecture: Question Period
2:15 Effects of Pallidotomy on the Parkinsonian Subthalamic Nucleus
Vasilios A. Zerris, MD, MSc; Jeff Arle, MD, PhD; Jay Shils, PhD; Ron Alterman, MD
2:27 STN DBS for Parkinson’s Disease: Are We Where We Think We Are?
Claudio Pollo, MD; Reto Meuli, MD, PhD; Francois Vingerhoets, MD; Joseph Ghika, MD; Philippe Maeder, MD; Jean-Guy Villemure, FRCS(C)
2:39 Unilateral Deep Brain Stimulation of the Subthalamic Nucleus
Roy A.E. Bakay, MD; Leo Verhagen, MD; Jean Arzbaecher, CNRN, MS, RN,; Diane Sierens, MD; Brian Myre, MD; Nick Verwey, MD
2:51 Variability in Position of the Subthalamic Nucleus Targeted by Magnetic Resonance Imaging and Microelectrode Recordings as Compared to Atlas Co-Ordinates
Patricia Littlechild, FRCS; Thelekat R.K. Varma, FRCS; Paul R. Eldridge, FRCS; Susan Fox, MD; Alan Forster, MD; Nick Fletcher, MD; Malcolm Steiger, MD; Patricia Byrne, RN; Kath Tyler, MSc; Sally Flintham, BSc
3:03 Refreshment Break
3:33 Synaptic Mechanism of Deep Brain Stimulation in Thalamus
Trent Anderson, PhD; Bin Hu, MD, PhD; Zelma HT Kiss, MD, PhD
3:45 Stimulation-Induced Mood Changes in Subthalamic Nucleus Deep Brain Stimulation, Location of the Cathodal Contact
Paul S. larson, MD; Gabriel Zada, BA; Matthew Mori, BA; Geoff Rau, BS; Efstathios Papavassiliou, MD; Susan Heath, MS, RN; Chadwick Christine, MD; William J. Marks, MD; Philip A. Starr, MD, PhD
3:57 Functional Outcomes After Gamma Knife Thalamotomy for Medically Refractive Tremor
John Y.K. Lee, MD; Ajay Niranjan, MD; Doug S. Kondziolka, MD; John C. Flickinger, MD; L. Dade Lundsford, MD
4:09 >Stereotactic Ventrooralis Thalamotomy for Task-Specific Focal Hand Dystonia (Writer’s Cramp)
Takaomi Taira, MD, PhD, Prof; Tomokatsu Hori, MD, PhD, Prof
4:21 A Novel Denervation Procedure for Idiopathic Cervical Dystonia
Takaomi Taira, MD, PhD, Prof; Tomokatsu Hori, MD, PhD, Prof
4:33 Pallidal Deep Brain Stimulation in Cervical Dystonia: Clinical Outcome in 4 Cases
Hazem A. Eltahawy, MD, FRCS; Andres M. Lozano, MD, PhD, FRCS(C)
4:45 Lesions Using DBS Electrodes: Experimental Studies in Fresh Egg Whites and in Human Cadavers
Sylvie Raoul, MD, PhD; Dominique Leduc, PhD; Roger Robert, MD; Jean-Michel Rogez, MD; Marie Garco, PhD; Joel Leborgne, MD; Youenn Lajat, MD; Andres M. Loazno, MD, PhD
5:00 BUSINESS MEETING/ELECTIONS
7:00 Gala Dinner Cruise
Wednesday, May 21 7:00 am Continental Breakfast
Session 7: Tumors
Chairs: Antonio DeSalles, MD, PhD and Michael Apuzzo, MD
7:30 Keynote Lecture: Where Are We Going?
Patrick J. Kelly, MD
8:05 Keynote Lecture: Question Period
8:15 Brain Metastases Radiosurgery: An Expanding Role in Cancer Management
Ajay Niranjan, MBBS; L. Dade Lunsford, MD; Douglas Kondziolka, MD; John M. Varlotto, MD; John C. Flickinger, MD
8:27 A Multi-Center Prospective Trial Evaluating a Miniature X-Ray Device for Interstitial Radiosurgery of Brain Metastases
Rees Cosgrove, MD, FRCS(C); David Porter, MD; Felix Senanayke, MD; Mark Bilsky, MD; Peter Black, MD, PhD; Jay Loeffler, MD; Nicholas Zervas, MD
8:39 Stereotactic Radiosurgery Compared to Surgery is Associated with the Reduced Risk of Leptomeningeal Spread in Patients with Posterior Fossa Metastases
Vitaly E. Siomin, MD; Andrew A. Kanner, MD; Shih-Yuan Lee, MHSA; John H. Suh, MD; Michael A. Vogelbaum, MD, PhD; Gene H. Barnett, MD
8:51 Stereotactic Brainstem Biopsy is Indicated for Diagnosis of a Diversity of Brainstem Pathology
Uzma Samadani, MD, PhD; Kevin D. Judy, MD
9:03 Combined Magnetic Resonance (MR)- and Positron Emission Tomography (PET)-Guided Radiosurgery for Brain Tumors: Experience of 46 Cases Treated with Leksell Gamma Knife (LGK)
Marc Levivier, MD, PhD; Nicolas Massager, MD; Jose Lorenzoni, MD; David Wikler, BS; Philippe David, MD; Daniel Devriendt, MD; Serge Goldman, MD, PhD; Jacques Brotchi
9:15 Phosphorus-32 Intracavitary Irradiation for Patients with Cystic Craniopharyngiomas
Constantinos G. Hadjipanayis, MD; Toshi Hasegawa, MD; Douglas Kondziolka, MD; L. Dade Lunsford, MD
9:27 Refreshment Break
10:15 Permanent Iodine-125 Interstitial Radiation Therapy in the Treatment of Non-GBM High-Grade Gliomas
Lucia Zamorano, MD; James Fontanesi, MD; Kenneth Levin, MD; Qinghang Li, MD; Fernando Diaz, MD
10:27 Aggressive Treatment of Cerebellar Brain Metastases Improves Outcome
Andrew A. Kanner, MD; Vitaly Siomin, MD; Gene H. Barnett, MD; Shih-Yuan Lee, MHSA; John H. Suh, MD; Michael A. Vogelbaum, MD, PhD
10:39 Integration of a Neurosurgical Image Guidance System and an Intraoperative MR-Scanner: The University Hospitals of Cleveland Experience
Robert J. Maciunas, MD; Dean David, PhD; Lewin Jonathan, MD; Duerk Jeffrey, PhD; Selman Warren, MD; Ratcheson A. Robert
10:51 CT-Guided Stereotactic Microsurgical Removal of Intraventricular Lesions Assisted by Endoscopy
Constantinos G. Hadjipanayis, MD; Anthony E. Harris, MD; L. Dade Lunsford, MD; Andrew K. Lunsford, MD; Amin Kassam, MD
11:03 Interstitial irradiation for CNS lesions
Guilherme Lepski, MD; Claudio Correia, PhD; Paulo Henrique Aguiar, PhD; Manoel Teixeira, PhD
11:15 From a Letterbox to a Keyhole Approach for Resecting Intracranial Brain Lesions
M. Sam Eljamel, MD; Monica Hofner, MD
11:27 Presurgical fMRI: Usefulness as Perceived by the Clinicians
Ann Tieleman, MD; Olivier Van Damme, MD; Karel Deblaere, MD; Jacques Caemaert, MD, PhD; Eric Achten, MD, PhD
11:39 Standard Imaging Protocol for fMRI
Samuel R. Browd, MD, PhD; William T. Couldwell, MD, PhD; James Lee, PhD
11:51 Lunch
Poster Viewing with Presenters
Wednesday, May 21 Session 8: Basic Science/Imaging
Chairs: Robert E. Gross, MD, PhD and Edmond Knopp, MD
7:30 am Keynote Lecture: How Does the Brain Work?
Rodolfo Llinas, MD, PhD
8:05 Keynote Lecture: Question Period
8:15 Keynote Lecture: Cerebral Microdialysis and Single Neuron Recordings in the Human Brain – What Have We Learned and Where Are We Going?
Itzhak Fried, MD, PhD
8:45 Use of Multichannel Auditory Brainstem Implant for Deafnessin Neurofibromatosis Type II
Marc S. Schwartz, MD; Steven R. Otto, MA; Derald E. Brackmann, MD; William E. Hitselberger, MD; Robert V. Shannon, PhD
8:57 Brain Machine Interfaces: Functional and MRI-Guided Placementof High-Density Microelectrode Arrays in the Study of Movement in Non-Human Primates
Parag G. Patil, MD, PhD; Dennis A. Turner, MD, MA; Miguel A.L. Nicolelis, MD
9:09 Stereotactic Accuracy of a 3 Tesla Magnetic Resonance Imaging Unit
Hooman Azmi, MD; Michael Schulder, MD
9:21 High Yield Differentiation of Neurons from Rat Neural Progenitor Cells
Elizabeth C.Tyler-Kabara, MD, PhD; Yongjian Liu, PhD; Glenn Gobbel, PhD; Douglas Kondziolka, MD, FACS, FRACS, MSc
9:33 Refreshment Break
10:15 New Instrumentation for Electrophysiologically-Guided Delivery of Microvolumes of Therapeutic
Miles G. Cunningham, MD, PhD; Hayrunnisa Bolay, MD, PhD; Douglas Jacoby, PhD; Michael Moskowitz, PhD; Charles Scouten, PhD; Christopher Moore, PhD
10:27 Differentiation of Human Embryonic Stem Cell-Derived Neural >Precursors Following Transplantation into the Immunodeficient Mouse Brain
Daniel J. Guillaume, MD; Su-Chun Zhang, MD, PhD
10:39 Anterior Mesiotemporal Lobe Activation Detected with fMRI: >Preliminary Results
Karel Deblaere, MD; Ann Tieleman, MD; Pieter Vandemaele; Kristel Vonck, MD; Guy Vingerhoets, PhD; Paul Boon, Md, PhD; Eric Achten, MD, PhD
10:51 A Quick, and Universal Method for Stereotactic Visualization of the Subthalamic Nucleus Before and After Implantation of Deep Brain Stimulation Electrodes
Marwan I. Hariz, MD, PhD, Prof; Paul Krack, MD, PhD; Roger Melvill, MD; Jan V. Jorgensen, MD; Wolfgang Hamel, MD; Hidehiro Hirabayashi, MD, PhD; Mathieu Lenders, MD; Nils Wesslen, MD, PhD; Magnus Tengvar, MD; Tarek Yousry, MD, PhD, Prof
11:03 Experience Using Frameless Navigation in 646 Epilepsy Surgery Cases
Werner K. Doyle, MD
11:15 Corpus Callosotomy in Children: A Review of 15 Cases
Gustavo Luzardo-Small, MD; Lamar Davis, BS; V.V. Vedanarayanan, MD; Mecheri Sundaram, MD; Colette Parker, MD; Owen Evans, MD; John A. Lancon, MD
11:27 Effect of Stereotactic High-Frequency Stimulation in the Anterior Lobe of Cerebellum in Cerebral Palsy
Miroslav Galanda, MD, PhD; Stanislav Horvath, PhD
11:39 Correlation Between Peroperative STN Neurophysiology
Lazorthes Yves, MD; Cintas Pascal, MD; Simonetta-Moreau Marion, MD; Breffel-Courbon Christine, MD; Fabre Nelly, MD; Ory Fabienne, MD; Chaynes Patrick, MD; Sabatier Jean, MD; Rascol Olivier, MD; Berry Isabelle, MD
11:51 Deep Brain Stimulation in Parkinson’s Disease: Association Between Stimulation Parameters and Cognitive Performance
Paul Francel, MD; Kersi J. Bharucha, MD; Alan Stevens, BS; Katherine A. Ryder, MS; Jeffrey Wetmore, BS; James G. Scott, PhD
12:05 pm Lunch
Poster Viewing with Presenters
Wednesday, May 21 Session 9: Epilepsy
Chairs: David W. Roberts, MD and Andre Olivier, MD, PhD
1:30 pm Keynote Lecture: What’s New In Epilepsy Surgery
Dennis D. Spencer, MD
2:05 Keynote Lecture: Question Period
2:15 Subtraction Ictal SPECT Co-Registered to MRI (SISCOM) in theLong Term Outcome for Repeat Epilepsy Surgery
Nicholas M. Wetjen, MD; Gregory D. Cascino, MD; A. James Fessler, MD; Elson L. So, MD; Denise M. Cambier, MD; Terence J. O’Brien, MBBS; Brian P. Mullan, MD; W. Richard Marsh, MD
2:27 Chronic Electrical Stimulation (CES) of Bilateral Hippocampal Foci in the Treatment of Temporal Lobe Seizures
Ana L. Velasco, MD; Marcos Velasco, PhD; Beatriz Rojas, BSc; Jose A. Hernandez, MSc; Martha L. Perez, BSc; Francisco Velasco, MD
2:39 Complications and Outcome in 296 Vagus Nerve Stimulator Procedures for Epilepsy
Werner K. Doyle, MD
2:51 New Modified Treatment Method in MTLE Radiosurgery – Based on the Evaluation of 23 MTLE Cases in Marseille Timone Hospital
Motohiro Hayashi, MD; Jean Regis, MD; Taku Ochiai, MD; Fumitaka Yamane, MD; Tomokatsu Hori, MD
3:03 Refreshment Break
3:30 A 10 Year Experience with Magnetic Source Imaging in the Guidance of Epilepsy Surgery
Joseph R. Smith, MD; Don W. King, MD; Yong D. Park, MD
3:42 Optical Imaging of Epileptiform Events in an Acute In Vivo Model
Ashesh D. Mehta, MD, PhD; Suh Minah, PhD; Bahar Sonya, PhD; Schwartz H. Theodore, MD
3:54 Epilepsy Surgery for Cortical Dysplasia (CD): Outcome and Efficacy of Moderate to Severe CD
Werner K. Doyle, MD
4:06 Selective Amygdalo-Hippocampectomy in Temporal Lobe Epilepsy: Results in 200 Patients
Andre Olivier, MD, PhD; F. Andermann, MD; F. Dubeau, MD; Aviva Abosch, MD; N. Poulin, MD; W. Boling, MD
4:18 Operative Technique and Results of Subtemporal Amygdalohippocampectomy for Medically Intractable Medial Temporal Lobe Epilepsy
Tomokatsu Hori, MD, DMSc; Fumitaka Yamane, MD, DMSc; Taku Ochiai, MD; Motohiro Hayashi, MD, DMSc; Takaomi Taira, MD, DMSc
4:30 Implantation and Testing of Responsive NeuroStimulator (RNS)
Michael Munz, MD; Robert D. Sweazey, PhD; Carla Barrett, MS; Audra Plenys-Loftman, PhD; Harry Vinters, MD; Zaneta Popovska, BS; David A. Greene, BS
4:42 Peri Insular Hemispherotomy: Potential Pitfalls and Complication Avoidance
Roy T. Daniel, MS; Jean-Guy Villemure, FRCS(C)
Wednesday, May 21 Session 10: Radiosurgery
Chairs: Douglas Kondziolka, MD and Eban Alexander, MD
1:30 pm Keynote Lecture: Radiosurgery: Where Are We Heading?
L. Dade Lunsford, MD
2:05 Keynote Lecture: Question Period
2:15 Long-Term Results After Radiosurgery for Benign Brain Tumors
Douglas Kondziolka, MD; Narendra Nathoo, MD; John Flickinger, MD; Ajay Niranjan, MD; Ann Maita, MS; L. Dade Lunsford, MD
2:27 Radiation and Regeneration: Behavioral Improvement and GDNF Expression After Gamma Knife Radiosurgery in the 6-OHDA Model of Hemi-Parkinsonism
Vasilios A. Zarris, MD; Zhen Zheng, PhD; George Noren, MD; Arno Sungarian, MD; Gerhard Friehs, MD
2:39 Predictive Factors of Radiation Necrosis After Radiosurgery for Cerebral Metastases
Charles A. Valery, MD; Georges Noll, MD; Michel Duyme, PhD;Gilbert Boisseire, PhD; Jean-Jacques Mazeron, MD, PhD; Remy van Effenterre, MD; Philippe Cornu, MD
2:51 Analysis of Tumor Control Toxicity in Patients Who Have Survived at Least One Year After Radiosurgery for Brain Metastases
John M. Varlotto, MD; John C. Flickinger, MD; Ajay K. Bhatnagar, BA; Douglas Kondziolka, MD; Dad Lunsford, MD
3:03 Refreshment Break
3:30 Clinical Implementation of an Automated Planning System for Gamma Knife Radiosurgery
Lawrence S. Chin, MD; David M. Shepard, PhD; Steven J. DiBiase, MD; Shahid A. Naqvi, PhD; Jinho Lim, PhD; Michael C. Ferris, PhD
3:42 Stereotactic Radiosurgery of Skull Base Meningiomas – Tumour Metablism as Predictive Parameter
Peter Warnke, MD; Danny Fritzsche, MD; Ekkehard Kasper, MD, PhD; Christoph B. Ostertag, MD
3:54 MRI Changes in the Rat Hippocampus Following Proton Radiosurgery
Paul Chapman, MD; James Rabinov, MD; Jonathan Brisman, MD; Jay Loeffler, MD; Marc Bussiere, PhD; Patricia Lee; Gilberto Gonzalez, MD; Rees Cosgove, MD, FRCS(C)
4:06 Gamma Knife Radiosurgery in the Management of Brain Metastases from Lung Carcinoma: Factors Affecting Survival, Local Control and Freedom from New Brain Metastases/td>
Ajay Jawahar, MD; Ronnie E. Matthew, BS; Beepti Shukla, MD; Brian K. Willis, MD, FACS; Donald R. Smith, MD; Federico Ampil, MD; Anil Nanda, MD, FACS
4:18 The Significance of Tumor Location in Gamma Knife Treatment for Meningiomas
Thomas F. Mindermann, MD; Olivier de Rougement
4:30 The Role of MRI and Proton MRS in Directing Leading Edge Boost Gamma Knife Radiosurgery for Recurrent Glioblastoma Multiforme
Christopher M. Duma, MD; Michael Brant-Zawadzki, MD; Michael Shea, MD; Jay Tassin, MD; Mackintosh Ralph, PhD; Plunkett Marianne, BSc; Sharp Shari, PA-C
4:45 CLOSING CEREMONIES